| Date | Location | Result | |
| 05-29-10 | Cary, N.C. | Southern Indiana 6, UC San Diego 4 | Box score |
| 05-28-10 | Cary, N.C. | Southern Indiana 3, Ga. Coll. & St. Univ 2 | Box score |
| 05-27-10 | Cary, N.C. | Ga. Coll. & St. Univ 3, Southern Indiana 0 | Box score |
| 05-25-10 | Cary, NC | Southern Indiana 7, Kutztown 1 | Box score |
| 05-23-10 | Cary, N.C. | Southern Indiana 8, Minnesota State 6 | Box score |
| 05-16-10 | Evansville, IN | Southern Indiana 11, Grand Valley State 4 | Box score |
| 05-16-10 | Evansville, IN | Southern Indiana 7, Grand Valley State 3 | Box score |
| 05-15-10 | Evansville, IN | Southern Indiana 6, Northern Kentucky 5 | Box score |
| 05-15-10 | Evansville, IN | Grand Valley State 6, Southern Indiana 3 | Box score |
| 05-14-10 | Evansville, IN | Southern Indiana 12, Wayne State 10 | Box score |
| 05-13-10 | Evansville, IN | Southern Indiana 9, Indianapolis 6 | Box score |
| 05-09-10 | Sauget, IL | Southern Indiana 4, Bellarmine 2 | Box score |
| 05-08-10 | Sauget, IL | Southern Indiana 16, Indianapolis 2 | Box score |
| 05-07-10 | Sauget, IL | Southern Indiana 10, Rockhurst 3 | Box score |
| 05-06-10 | Sauget, IL | Southern Indiana 11, Lewis 3 | Box score |
| 05-02-10 | Quincy, Illinois | Southern Indiana 10, Quincy 3 | Box score |
| 05-02-10 | Quincy, Illinois | Southern Indiana 9, Quincy 1 | Box score |
| 05-01-10 | Quincy, Illinois | Southern Indiana 8, Quincy 7 | Box score |
| 05-01-10 | Quincy, Illinois | Southern Indiana 10, Quincy 5 | Box score |
| 04-24-10 | Rensselaer, IN | Southern Indiana 6, Saint Joseph's (IN) 3 | Box score |
| 04-24-10 | Rensselaer, IN | Saint Joseph's (IN) 7, Southern Indiana 3 | Box score |
| 04-20-10 | Evansville, IN | Evansville 8, Southern Indiana 2 | Box score |
| 04-18-10 | Evansville, IN | Southern Indiana 12, Missouri S&T 6 | Box score |
| 04-18-10 | Evansville, IN | Missouri S&T 8, Southern Indiana 6 | Box score |
| 04-17-10 | Evansville, IN | Southern Indiana 16, Missouri S&T 10 | Box score |
| 04-16-10 | Evansville, IN | Southern Indiana 12, Missouri S&T 0 | Box score |
| 04-14-10 | Highland Heights, KY | Northern Kentucky 9, Southern Indiana 5 | Box score |
| 04-14-10 | Highland Heights, KY | Southern Indiana 6, Northern Kentucky 5 | Box score |
| 04-11-10 | Kansas City, MO | Southern Indiana 6, Rockhurst 0 | Box score |
| 04-11-10 | Kansas City, MO | Southern Indiana 11, Rockhurst 8 | Box score |
| 04-10-10 | Kansas City, MO | Southern Indiana 11, Rockhurst 0 | Box score |
| 04-10-10 | Kansas City, MO | Southern Indiana 15, Rockhurst 7 | Box score |
| 04-08-10 | Evansville, IN | Southern Indiana 15, Oakland City 4 | Box score |
| 04-03-10 | Evansville, IN | Drury 3, Southern Indiana 2 | Box score |
| 04-03-10 | Evansville, IN | Southern Indiana 5, Drury 1 | Box score |
| 04-02-10 | Evansville, IN | Southern Indiana 4, Drury 3 | Box score |
| 04-02-10 | Evansville, IN | Southern Indiana 5, Drury 4 | Box score |
| 03-30-10 | Evansville, IN | Southern Indiana 10, Indiana Southeast 5 | Box score |
| 03-29-10 | St. Louis, MO | Southern Indiana 10, Maryville 6 | Box score |
| 03-29-10 | St. Louis, MO | Southern Indiana 6, Maryville 0 | Box score |
| 03-27-10 | St. Louis, MO | Southern Indiana 7, Maryville 1 | Box score |
| 03-27-10 | St. Louis, MO | Southern Indiana 8, Maryville 1 | Box score |
| 03-24-10 | Evansville, IN | Southern Indiana 14, Oakland City 4 | Box score |
| 03-23-10 | St. Louis, MO | Southern Indiana 8, Missouri-St. Louis 2 | Box score |
| 03-23-10 | St. Louis, MO | Southern Indiana 15, Missouri-St. Louis 3 | Box score |
| 03-20-10 | Evansville, IN | Southern Indiana 12, Missouri-St. Louis 11 | Box score |
| 03-19-10 | Evansville, IN | Southern Indiana 12, Missouri-St. Louis 0 | Box score |
| 03-17-10 | Louisville, Ky. | Southern Indiana 7, Bellarmine 3 | Box score |
| 03-14-10 | Evansville, IN | Southern Indiana 9, Kentucky Wesleyan 5 | Box score |
| 03-14-10 | Evansville, IN | Kentucky Wesleyan 14, Southern Indiana 7 | Box score |
| 03-13-10 | Evansville, IN | Southern Indiana 8, Indianapolis 7 | Box score |
| 03-12-10 | Evansville, IN | Indianapolis 12, Southern Indiana 10 | Box score |
| 03-10-10 | Evansville, IN | Bellarmine 7, Southern Indiana 4 | Box score |
| 03-08-10 | Evansville, IN | Southern Indiana 4, Wayne State (NE) 3 | Box score |
| 03-07-10 | Evansville, IN | Southern Indiana 12, Wayne State (NE) 1 | Box score |
| 03-06-10 | Evansville, IN | Southern Indiana 7, Wisconsin-Parkside 6 | Box score |
| 03-05-10 | Evansville, IN | Wisconsin-Parkside 7, Southern Indiana 2 | Box score |
| 02-28-10 | Evansville, IN | Southern Indiana 15, Tiffin 11 | Box score |
| 02-27-10 | Evansville, IN | Southern Indiana 11, Tiffin 7 | Box score |
| 02-27-10 | Evansville, IN | Southern Indiana 5, Tiffin 0 | Box score |
| 02-20-10 | Russellville, AR | Mo. Western State 4, Southern Indiana 3 | Box score |
| 02-20-10 | Russellville, AR | Mo. Western State 9, Southern Indiana 6 | Box score |
| 02-18-10 | Russellville, AR | Southern Indiana 12, Arkansas Tech 6 | Box score |
| 02-14-10 | Savannah, Ga. | Armstrong Atlantic 8, Southern Indiana 7 | Box score |
| 02-14-10 | Savannah, Ga. | Southern Indiana 7, Armstrong Atlantic 3 | Box score |
| 02-13-10 | Savannah, Ga. | Southern Indiana 8, Armstrong Atlantic 5 | Box score |